The upcoming discussion will update you about the differences between Smooth Endoplasmic Reticulum and Rough Endoplasmic Reticulum.

Difference # Smooth Endoplasmic Reticulum:

1. SER does not bear ribosomes over the surface of its membranes.

2. It is mainly formed of vesicles and tubules.

3. It is engaged in the synthesis of glycogen, lipids and steroids.

4. SER gives rise to sphareosomes.

5. Pores are absent so that materials synthesized by SER do not pass into its channels.

6. SER is often peripheral. It may be connected with plasma lemma.

7. Ribophorins are absent.

8. It may develop from RER.

9. It has enzymes for detoxification.

10. Vesicles for cis- face of Golgi apparatus are provided by SER.

Difference # Rough Endoplasmic Reticulum:

1. RER possesses ribosomes attached to its membranes.

2. It is mainly formed of cisternae and a few tubules.

3. The reticulum takes part in the synthesis of proteins and enzymes.

4. It helps in the formation of lysosomes through the agency of Golgi apparatus.

5. RER possesses narrow pores below its ribosomes for the passage of synthesized polypeptides into ER channels.

6. It is often internal and connected with nuclear envelope.

7. RER contains Ribophorins for providing attachment to ribosomes.

8. It may develop from nuclear envelope.

9. The same are absent.

10. It provides bio-chemicals for Golgi apparatus.

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