The upcoming discussion will update you about the differences between Apo-Enzyme and Co-Enzyme.

Difference # Apo-Enzyme:

1. It is protein part of the holoenzyme or con­jugate enzyme.

2. It is large in size.

3. An apoenzyme is specific for an enzyme.

4. It takes part in only catalytic activity of the enzyme.

5. Apoenzyme does not help in group transfer.

6. Apoenzyme is thermolabile.

Difference # Co-Enzyme:

1. Coenzyme is the non-protein organic group which gets attached to the apoenzyme to form holoenzyme or conjugate enzyme.

2. It is small in size.

3. A coenzyme can function as a cofactor for a number of enzymes carrying out that particular type of reaction.

4. It helps in removing a product of chemical reaction besides bringing contact between the substrate and the enzyme.

5. Coenzyme takes part in group transfer.

6. Coenzyme is heat stable.

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