The upcoming discussion will update you about the difference between active immunity and passive immunity.

Difference # Active Immunity:

1. Active immunity is produced actively by host’s immune system as a result of the stimulation by antigen.

2. Active immunity is induced by microbial infection or by contact with antigens.

3. Active immunity lasts long.

4. Active immunity is effective only a period of time required for generating antibodies and/or immunocompetent cells. This period of time is called tag period.

5. There is often a ‘negative phase’ during active immunity development. During negative phase the level of measurable immunity is lower than before amigenic stimulus.

6. Active immunity enjoys immunological memory due to which the subsequent challenge (secondary response) in host is more effective.

7. It proves to be more effective and confers better protection of the host.

8. Active immunity docs not work in immunodeficient hosts.

Difference # Passive Immunity:

1. Passive immunity is transferred from one host to another i.e., it is received passively by the host.

2. It is conferred by antibody-administration in host.

3. Passive immunity lasts short.

4. Passive immunity is effective immediately. It lacks any lag period.

5. Passive immunity does not possess any negative phase.

6. Passive immunity lacks immunological memory. Subsequent administration of antibodies is less effective due to immune elimination.

7. It is less effective and provides comparatively inferior protection of the host

8. Passive immunity works in immunodeficient hosts.

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