The upcoming discussion will update you about the difference between active immunity and passive immunity.

Difference # Active Immunity:

1. Host participation:

Produced actively by the immune system of host.

2. Activation:

Induced by infection or by contact with immunogen.

3. Duration of effectivity:

Immune response-durable and effective.

4. Time:

Immunity effective only after lag period.

5. Memory:

Immunological memory present.

6. Duration:

Subsequent challenge with booster dose more effective.

7. Negative phase:

After antigenic stimulus, negative phase may occur due to antigen combining with any pre-existing antibody in blood.

8. Purpose:

Serves no purpose in immuno deficient host.

9. Uses:

Used for prophylaxis to increase body resistance.

Difference # Passive Immunity:

1. Host participation:

Received passively by the host; no active host participation.

2. Activation:

Conferred by introduction of ready- made antibodies.

3. Duration of effectivity:

Immune response—short lived and less effective.

4. Time:

Immediate immunity.

5. Memory:

No immunological memory.

6. Duration:

Subsequent administration of anti­body less effective due to immune elimination.

7. Negative phase:

No negative phase.

8. Purpose:

Applicable in immuno deficient host.

9. Uses:

Used for treatment of acute infection.

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