In this article we will discuss about the examples of pedigree pattern of autosomal and sex chromosomal genetic diseases. 1. Pedigree pattern of an autosomal dominant trait. Note the vertical pattern of inheritance. Solid squares and circles indicating the affected males and females while hollow squares and circles are unaffected males and females. 2. Pedigree patterns of an autosomal recessive [...]
In this article we will discuss about the Introduction and hypothesis of human gene evolution. Introduction to the Evolution of Human Gene: Some chromosomes appear to have been relatively protected from change during primate evolution, for example human chromosome 19 and X. By contrast other chromosomes have been prone to significant reorganization for example human chromosomes 1, 2, 3 and [...]
The MHC has been divided into three regions on the basis of structure, function and alloreactivity of the gene products, which-are: 1. Class - I at the telomeric ends 2. Class - II at the centromeric ends 3. Class - III, which is located between class - I and II regions. The classic class I and II genes code for [...]