In this article we will discuss about the Introduction and hypothesis of human gene evolution. Introduction to the Evolution of Human Gene: Some chromosomes appear to have been relatively protected from change during primate evolution, for example human chromosome 19 and X. By contrast other chromosomes have been prone to significant reorganization for example human chromosomes 1, 2, 3 and [...]
In this article we will discuss about the examples of pedigree pattern of autosomal and sex chromosomal genetic diseases. 1. Pedigree pattern of an autosomal dominant trait. Note the vertical pattern of inheritance. Solid squares and circles indicating the affected males and females while hollow squares and circles are unaffected males and females. 2. Pedigree patterns of an autosomal recessive [...]
This article provides an overview on the principles of gene transfer. Classical gene therapies normally require efficient transfer of cloned genes into disease cells so that the introduced genes are expressed at suitably high levels. In principle, there are numerous different physicochemical and biological methods that can be used to transfer exogenous genes into human cells. The size of DNA [...]