In this article we will discuss about the principles and applications of gene therapy based on targeted inhibition of gene expression in vivo. Principles and Applications of Therapy Based on Targeted Inhibition of Gene Expression In Vivo: One way of treating certain human disorders is to selectively inhibit the expression of a predetermined gene in vivo. In principle, this general [...]
Let us make an in-depth study of the gene therapy principles for neoplastic disorders and infectious diseases. Cancer Gene Therapies: Many different approaches can be used for cancer gene therapy (see Culver and Blaese, 1994 and Table 23.6) and, in marked contrast to the few gene therapy trials for inherited disorders, numerous cancer gene therapy trials are currently being conducted [...]
In this article we will discuss about the different strategies foe gene therapy. The term gene therapy is a broad one: it encompasses many different strategies, all of which are designed to overcome or alleviate disease by a procedure in which genes, gene segments or oligonucleotides are introduced into the cells of an affected individual. The genetic material may be [...]