Archive | Gene Therapy

Gene Therapy & Neoplastic Disorders | Human Genetics

Let us make an in-depth study of the gene therapy principles for neoplastic disorders and infectious diseases. Cancer Gene Therapies: Many different approaches can be used for cancer gene therapy (see Culver and Blaese, 1994 and Table 23.6) and, in marked contrast to the few gene therapy trials for inherited dis­orders, numerous cancer gene therapy trials are currently being conducted [...]

By |2016-12-12T07:34:22+00:00December 12, 2016|Gene Therapy|Comments Off on Gene Therapy & Neoplastic Disorders | Human Genetics
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Gene Therapy Strategies & HIV-1 Life-Cycle | Human Genetics

Let us make an in-depth study of the gene therapy strategies designed to interfere with the HIV-1 life-cycle. Basically Inhibition has been Envisaged at Three Major Levels: (i) Blocking HIV-1 infection: HIV-1 normal­ly infects T lymphocytes by binding of the viral gp120 envelope protein to the CD4 receptor on the cell membrane. Transfer of a gene encoding a soluble form [...]

By |2016-12-12T07:34:22+00:00December 2, 2016|Gene Therapy|Comments Off on Gene Therapy Strategies & HIV-1 Life-Cycle | Human Genetics
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