In this article we will discuss about the examples of pedigree pattern of autosomal and sex chromosomal genetic diseases. 1. Pedigree pattern of an autosomal dominant trait. Note the vertical pattern of inheritance. Solid squares and circles indicating the affected males and females while hollow squares and circles are unaffected males and females. 2. Pedigree patterns of an autosomal recessive [...]
In this article we will discuss about the Introduction and hypothesis of human gene evolution. Introduction to the Evolution of Human Gene: Some chromosomes appear to have been relatively protected from change during primate evolution, for example human chromosome 19 and X. By contrast other chromosomes have been prone to significant reorganization for example human chromosomes 1, 2, 3 and [...]
In this article we will discuss about the development of tumour suppressor genes. Inactivation of tumour suppressor genes also contributes to development of tumours. Normally, tumour suppressor genes act to inhibit cell proliferation and tumour development. When these genes are inactivated or lost they lead to abnormal proliferation of tumour cells. The first tumour suppressor gene was identified through studies [...]