In this article we will discuss about causes for the oncogenicity of the oncogene. When the oncogene from human bladder carcinoma cells was sequenced, and its sequence was compared with the sequence of the homologous proto-oncogene, its oncogenicity was found to result from a single base pair substitution. That is, a single base pair difference was shown to correlate with [...]
In this article we will discuss about the analysis of the human genome. Molecular analyses of medical relevance rely heavily on four strategic features: (1) The ability to clone and characterize nucleic acid sequences, (2) The specificity of nucleic acid hybridization, (3) The specificity of restriction endonucleases, and (4) The power of DNA amplification using the polymerase chain reaction (PGR). [...]
In this article we will discuss about the top two types of inherited diseases that are found in families. The diseases are: 1. Diabetes Mellitus 2. Muscular Dystrophies. Disease # 1. Diabetes Mellitus: This is a complex, heterogeneous condition which is frequently seen to recur in certain families. It is due to partial or complete lack of insulin which leads [...]