In this article we will discuss about the principles and applications of gene therapy based on targeted inhibition of gene expression in vivo. Principles and Applications of Therapy Based on Targeted Inhibition of Gene Expression In Vivo: One way of treating certain human disorders is to selectively inhibit the expression of a predetermined gene in vivo. In principle, this general [...]
In this article we will discuss about the examples of pedigree pattern of autosomal and sex chromosomal genetic diseases. 1. Pedigree pattern of an autosomal dominant trait. Note the vertical pattern of inheritance. Solid squares and circles indicating the affected males and females while hollow squares and circles are unaffected males and females. 2. Pedigree patterns of an autosomal recessive [...]
In this article we will discuss about the Introduction and hypothesis of human gene evolution. Introduction to the Evolution of Human Gene: Some chromosomes appear to have been relatively protected from change during primate evolution, for example human chromosome 19 and X. By contrast other chromosomes have been prone to significant reorganization for example human chromosomes 1, 2, 3 and [...]