After reading this article you will learn about: 1. Definition and Need of Metabolism 2. Types of Metabolism. Definition and Need of Metabolism: Metabolism is a process of alteration of drugs in the body so as to modify their activity and structure. If lipophylic drugs are not metabolized it will be reabsorbed by the kidney tubule and will circulate in [...]
This article throws light upon the four main terms related to agonist-antagonist interactions. They are: 1. PKX 2. PAX 3. PD’x 4. PDX. Term # 1. PKX: This is an expression for affinity and is defined as negative logarithm of the molar concentration of a drug that elicits an effect representing x% of the maximal response the drug can produce. [...]
This article throws light upon the three main types of pharmacokinetic variables of drugs. The variables are: 1. Plasma Half-Life (t1/2β) 2. Volumes of Distribution 3. Total Body Clearance (CIB). Type # 1. Plasma Half-Life (t1/2β): Half-life is defined as the time of declining the initial plasma drug concentration by half. It is also known as the half-time of elimination [...]