This article throws light upon the three main routes of drug administration. The routes are: 1. Topical or External Application 2. Oral or Enteral Route 3. Parenteral Route (Injection). Route # 1. Topical or External Application: The drugs administration by this route generally affects to the part to which they are applied. However, some drugs applied topically are absorbed from [...]
After reading this article you will learn about:- 1. Factors Affecting Blood Concentration of a Drug 2. Absorption of Drug 3. Distribution 4. Dosage Forms 5. Nome nclature 6. Bioavailability 7. Apparent Volume of Distribution (VP) 8. Excretion. Factors Affecting Blood Concentration of a Drug: The following factors can affect the blood concentrations of a drug: (i) The route of [...]
This article throws light upon the eight main physiological factors that affect the rate of drug absorption. The factors are: 1. Passage of Drug Molecule Across Membranes 2. pKa 3. pH - pka Partion Concept 4. pH-Partition Hypothesis 5. Active Transport 6. Facilitated Diffusion 7. Pinocytosis (Vesicular Transport) 8. Pore or Convective Transport. Physiologic Factor # 1. Passage of Drug [...]