After reading this article you will learn about: 1. Definition and Need of Metabolism 2. Types of Metabolism. Definition and Need of Metabolism: Metabolism is a process of alteration of drugs in the body so as to modify their activity and structure. If lipophylic drugs are not metabolized it will be reabsorbed by the kidney tubule and will circulate in [...]
After reading this article you will learn about the dosage regimen of a drug. Many drugs like antibiotics, cardio tonics, anticonvulsants, hormones etc. are generally given in a multiple-dosage for prolonged therapeutic effect. The plasma concentrations of these drugs must be maintained within narrow limits to achieve maximal clinical effectiveness. A dosage regimen must be established for each drug to [...]
Kinetic 'order' is a term which simply means that the various processes are ranked in order of increasing complexity. The important kinetic processes which are concerned are those governing the entry of the drug into the blood, its distribution in body tissues, and its elimination from the blood by metabolism and excretion. Such processes are generally of 'zero-order' or 'first-order'. [...]