After reading this article you will learn about:- 1. Factors Affecting Blood Concentration of a Drug 2. Absorption of Drug 3. Distribution 4. Dosage Forms 5. Nome nclature 6. Bioavailability 7. Apparent Volume of Distribution (VP) 8. Excretion. Factors Affecting Blood Concentration of a Drug: The following factors can affect the blood concentrations of a drug: (i) The route of [...]
This article throws light upon the eight main physiological factors that affect the rate of drug absorption. The factors are: 1. Passage of Drug Molecule Across Membranes 2. pKa 3. pH - pka Partion Concept 4. pH-Partition Hypothesis 5. Active Transport 6. Facilitated Diffusion 7. Pinocytosis (Vesicular Transport) 8. Pore or Convective Transport. Physiologic Factor # 1. Passage of Drug [...]
After reading this article you will learn about: 1. Definition and Need of Metabolism 2. Types of Metabolism. Definition and Need of Metabolism: Metabolism is a process of alteration of drugs in the body so as to modify their activity and structure. If lipophylic drugs are not metabolized it will be reabsorbed by the kidney tubule and will circulate in [...]