This article throws light upon the four main terms related to agonist-antagonist interactions. They are: 1. PKX 2. PAX 3. PD’x 4. PDX. Term # 1. PKX: This is an expression for affinity and is defined as negative logarithm of the molar concentration of a drug that elicits an effect representing x% of the maximal response the drug can produce. [...]
This article throws light upon the three main types of pharmacokinetic variables of drugs. The variables are: 1. Plasma Half-Life (t1/2β) 2. Volumes of Distribution 3. Total Body Clearance (CIB). Type # 1. Plasma Half-Life (t1/2β): Half-life is defined as the time of declining the initial plasma drug concentration by half. It is also known as the half-time of elimination [...]
This article throws light upon the three main ways for expressing percentage concentration in a drug. The ways are: 1. Weight in Weight (W/W) 2. Weight in Volume (W/V) 3. Volume in Volume (V/V). Way # 1. Weight in Weight (W/W): This expression is used when solids are mixed with solids e.g. in powders, paste, ointments etc. A 5% w/w [...]