After reading this article you will learn about the role and functions of second messengers. Many hormones, neurotransmitters, autacoids and drugs act on specific membrane receptors, the immediate consequence of which is activation of a cytoplasmic component of the receptor, which may be an enzyme such as adenylate cyclase, guanylate cyclase or activation of a transport systems or opening of [...]
This article throws light upon the four main types of receptors. The types are: 1. Receptors for Fast Neurotransmitters 2. Receptor for many Hormones and Slow Transmitters 3. Receptors for Insulin and Various Growth-Factors 4. Steroid Receptors. Type # 1. Receptors for Fast Neurotransmitters: These are coupled directly to an ion- channel. These receptors are involved mainly in fast synaptic [...]
This article throws light upon the three main types of pharmacokinetic variables of drugs. The variables are: 1. Plasma Half-Life (t1/2β) 2. Volumes of Distribution 3. Total Body Clearance (CIB). Type # 1. Plasma Half-Life (t1/2β): Half-life is defined as the time of declining the initial plasma drug concentration by half. It is also known as the half-time of elimination [...]