After reading this article you will learn about the concept and types of pharmacokinetic models. Concept of Pharmacokinetic Models: Drugs remain in dynamic state within the body and drug events often happen simultaneously. In order to describe a complex biologic system, assumptions are made concerning the movement of drugs. The mathematical models are used to describe the absorption, distribution and [...]
After reading this article you will learn about the dosage regimen of a drug. Many drugs like antibiotics, cardio tonics, anticonvulsants, hormones etc. are generally given in a multiple-dosage for prolonged therapeutic effect. The plasma concentrations of these drugs must be maintained within narrow limits to achieve maximal clinical effectiveness. A dosage regimen must be established for each drug to [...]
Kinetic 'order' is a term which simply means that the various processes are ranked in order of increasing complexity. The important kinetic processes which are concerned are those governing the entry of the drug into the blood, its distribution in body tissues, and its elimination from the blood by metabolism and excretion. Such processes are generally of 'zero-order' or 'first-order'. [...]