After reading this article you will learn about: 1. Definition and Need of Metabolism 2. Types of Metabolism. Definition and Need of Metabolism: Metabolism is a process of alteration of drugs in the body so as to modify their activity and structure. If lipophylic drugs are not metabolized it will be reabsorbed by the kidney tubule and will circulate in [...]
After reading this article you will learn about the concept and types of pharmacokinetic models. Concept of Pharmacokinetic Models: Drugs remain in dynamic state within the body and drug events often happen simultaneously. In order to describe a complex biologic system, assumptions are made concerning the movement of drugs. The mathematical models are used to describe the absorption, distribution and [...]
After reading this article you will learn about the dosage regimen of a drug. Many drugs like antibiotics, cardio tonics, anticonvulsants, hormones etc. are generally given in a multiple-dosage for prolonged therapeutic effect. The plasma concentrations of these drugs must be maintained within narrow limits to achieve maximal clinical effectiveness. A dosage regimen must be established for each drug to [...]