Each attack of fever shows three successive stages:
i. Cold stage:
At the beginning of malaria fever the patient suffers from a severe shaking chill.
ii. Hot stage:
As the chill subsides, the body temperature rises as high as 41° C or 106° F.
iii. Sweating stage: D
As the temperature lowers down, the patient sweats profusely. Malaria fever takes place when schizonts in RBC burst, liberating the merozoites and haemozoin (malarial pigment) in the blood plasma. This haemozoin is said to be toxic and so induces high fever with shivering. It is important to note that bursting of schizonts tends to be synchronous as they all burst at the same time.
