In this article we will discuss about the function of regulator gene. The genetic basis for induction and repression was studied for several years by Jacob and Monod at the Pasteur Institute in Paris. They investigated regulation of the activities of genes which control fermentation of lactose through synthesis of the enzyme β-galactosidase in E. coli. They were awarded Nobel [...]
The Genetic Code: The four letter language of nucleic acids is translated into the twenty letter language of the proteins viz the genetic code. The early genetic experiments indicated that each amino acid is coded for by a certain number of successive nucleotides in DNA. The best way of deciphering the genetic code therefore would be to compare the nucleotide [...]
In this article we will discuss about the structure of nucleosome. When chromatin or whole chromosomes are spread on an air-water interface and examined in the electron microscope, fibers 250 Å in diameter are observed. These are de-oxy-nucleoprotein fibres in which DNA is complexed with protein. Removal of proteins by various methods reveals the 10 nm fibre (1nm = 10 [...]