In this article we will discuss about the translation of amino acid to tRNA in cytoplasm. (i) Activation of Amino acids: Amino acids must be necessarily activated before their involvement in peptide synthesis (Fig. 4-10). The process is accomplished by the binding of an amino acid to ATP enzymatically and its consequent transference to tRNA. (ii) Transfer of amino acid [...]
The below mentioned article provides a short note on the aminoacylation of tRNA. Role of Transfer RNA: Transfer RNA molecules play a key role in the process by delivering amino acids to the ribosome in an order specified by the mRNA sequence; this ensures that the amino acids are joined together in the correct order. Cells usually contain many species [...]
The following points highlight the three main stages for translation of RNA and protein synthesis. The stages are: 1. Initiation of Polypeptide 2. Elongation of Polypeptide: 3. Termination of Polypeptide. Translation of RNA: Stage # 1. Initiation of Polypeptide: Ribosomes exist as separate large and small subunits. The first step in translation involves the binding of the small ribosomal subunit [...]