The following points highlight the four methods to detect and isolate mutants. The methods are: 1. Replica Plating Technique 2. Resistance Selection Method 3. Substrate Utilization Method 4. Carcinogenicity Test. 1. Replica Plating Technique: Lederberg and Lederberg (1952) have given replica plating technique. This technique is used to detect auxotrophic mutants which differentiates between mutants and wild type strains on [...]
In this article we will discuss about:- 1. Meaning of Mutations 2. Occurrence of Mutations 3. Expression. Meaning of Mutations: Inheritance is based on genes that are faithfully transmitted from generation to generation in microorganisms (in all organisms). Despite the biochemical mechanisms that facilitate such transmissions faithfully, sudden change in the sequence of nucleotide bases in genes can and do [...]
Here is a compilation of notes on Gene Mutation. After reading these notes you will learn about: 1. Introduction to Gene Mutation 2. Origin of Gene Mutation 3. Effects 4. Direction 5. Types 6. Induction 7. Molecular Basis 8. Detection 9. Importance. Contents: Notes on Introduction to Gene Mutation Notes on the Origin of Gene Mutation Notes on the Effects [...]