Get the answer of: Does Z-DNA Play a Regulatory Role? One of the more interesting discoveries of the last decade was that segments of DNA that have sequences in which purines and pyrimidines alternate along each strand can form left-handed double helices. The Watson-Crick B-form of DNA is a right-handed double helix. The novel left-handed double-helical form of DNA has [...]
In this article we will discuss about the structure of chromatin in the light of nucleosome. Preamble: A supercoil model for chromatin structure was originally described by Pardon and Wilkins in 1972. Later studies of Boldwin (1975), Kornberg (1974) and others have shown that such a sub-unit structure of chromatin is not only present in mammalian cells but also found [...]
In this article we will discuss about the structure of lac operon in E. coli. The lac operon comprises three structural genes (z, y & a) and produces a polycistronic mRNA (Lac mRNA). This messenger RNA codes for β-galactosidase, lac permease and transacetylase. The lac permease is a single unit protein that acts as a carrier for the entrance of [...]