In this article we will discuss about the mechanism of formation of somatic cell hybrids. It had been known since the 60's that somatic cells from the same or different species in culture could spontaneously fuse to form polyploid cells. The product of fusion was called homokaryon if the two parental cells came from the same species, and heterokaryon or [...]
In this article we will discuss about the development of tumour suppressor genes. Inactivation of tumour suppressor genes also contributes to development of tumours. Normally, tumour suppressor genes act to inhibit cell proliferation and tumour development. When these genes are inactivated or lost they lead to abnormal proliferation of tumour cells. The first tumour suppressor gene was identified through studies [...]
In this article we will discuss about the top two types of inherited diseases that are found in families. The diseases are: 1. Diabetes Mellitus 2. Muscular Dystrophies. Disease # 1. Diabetes Mellitus: This is a complex, heterogeneous condition which is frequently seen to recur in certain families. It is due to partial or complete lack of insulin which leads [...]