In this article we will discuss about the structure of herpesviruses (explained with diagram). All of them are morphologically identical. They are large with a varying diameter from 140-170 nm. The nucleocapsid is spherical icosahedral and of about 100 nm diameter which is enclosed in a 30 nm thick glycoprotein lipid envelope. Thickness of the envelope indicates for the presence [...]
In this article we will discuss about the replication of herpesviruses. Sequential interaction takes place between specific viral membrane glycoproteins and cell membrane receptors (e.g. cell surface proteoglycans which are heparin sulphates). On the basis of complementary residues present on host cell and viral membrane, binding between virus and host cell membrane takes place before entering the virus within the [...]
In this article we will discuss about the assembly, evolvement and release of herpesviruses. Assembly of Herpesviruses: There are more than 30 HSV-1 gene products that act as the structural components of the virion. These are expressed with late kinetics. Capsid assembly i.e. enveloping is a complex process. The general outline of the process was established by careful electron microscopic [...]