In this article we will discuss about the meaning of tRNA. The genetic message contained in the nucleotide sequence of transcribed RNA cannot be read off directly by the amino acids in the polypeptide chain. Crick and Hoagland were first to postulate that an intermediate RNA molecule functions as an "adaptor" into which the amino acid is plugged so that [...]
In this article we will discuss about the meaning of reverse transcriptases. There are some cancer causing RNA viruses such as the Rous sarcoma virus (RSV) which produces cancer in chickens, avian myeloblastosis virus (AMV) causing leukemia in birds, and the mammary cancer and leukemia viruses in rodents. The viruses can cause heritable transformation of normal cells of animals and [...]
In this article we will discuss about the role of RNA polymerase in transcription. RNA polymerase enzymes are complex enzyme which in E. coli is made up of 5 subunits or polypeptide chains designated β, β', α, σ and ω with respective molecular weights of 160,000, 150,000, 90,000, 40,000 and 10,000. The α chain is present twice, others only once. [...]