The following components of deoxyribonucleotide (DNA) have been described: 1. A Five Carbon Ring 2. Nitrogenous Base 3. A Phosphate Group. 1. A Five Carbon Ring: Deoxyribose is a pentose sugar consisting of five carbon atoms. The first and fourth carbon atoms of this sugar combine with one oxygen atom and form a ring. The fifth atom (5') forms –CH2 [...]
In this article we will discuss about the X-ray crystallographic studies of DNA. In 1920, the basic chemical composition of nucleic acid was elucidated through the efforts of P.A. Levene. In 1940, for the first time W.T. Astbury gave first three dimensional structure of DNA model studied through X-ray crystallography. He concluded that its flat nucleotides get stacked to form [...]
The most common form of DNA which has right handed helix and proposed by Watson and Crick is called B-form of DNA or B-DNA. In addition, the DNA may be able to exist in other forms of double helical structure. These are A and C forms of double helix which vary from B- form in spacing between nucleotides and number [...]