In this article we will discuss about the repeated sequence of chromosomal DNA. Eukaryotic genomes contain large amount of repetitive sequences, sometimes present in hundreds or thousands of copies per genome. The understanding of repetitive sequences is based on studies conducted on denaturation (separation of DNA double helix into its two component strands) and renaturation (re-association of the single strands [...]
In this article we will discuss about the X-ray crystallographic studies of DNA. In 1920, the basic chemical composition of nucleic acid was elucidated through the efforts of P.A. Levene. In 1940, for the first time W.T. Astbury gave first three dimensional structure of DNA model studied through X-ray crystallography. He concluded that its flat nucleotides get stacked to form [...]
The below mentioned article provides notes on palindromic DNA. In the DNA molecule a variety of base sequences have been observed. Most of them do not have special features. The repeated sequences are of particular interest because they are the site of enzymatic activity and, sometimes give special features to the nucleic acid. For the first time Wilson and Thomas [...]