In this article we will discuss about the repeated sequence of chromosomal DNA. Eukaryotic genomes contain large amount of repetitive sequences, sometimes present in hundreds or thousands of copies per genome. The understanding of repetitive sequences is based on studies conducted on denaturation (separation of DNA double helix into its two component strands) and renaturation (re-association of the single strands [...]
The below mentioned article provides notes on palindromic DNA. In the DNA molecule a variety of base sequences have been observed. Most of them do not have special features. The repeated sequences are of particular interest because they are the site of enzymatic activity and, sometimes give special features to the nucleic acid. For the first time Wilson and Thomas [...]
In this article we will discuss about the Chargaff-equivalence rule for DNA. By 1948, a chemist Erwin Chargaff started using paper chromatography to analyse the base composition of DNA from a number of studies. In 1950, Chargaff discovered that in the DNA of different types of organisms the total amount of purines is equal to the total amount of pyrimidines [...]