In this article we will discuss about the Metabolism of Pyrimidine Nucleotides:- 1. Biosynthesis of Pyrimidine 2. Catabolism of Pyrimidine 3. Clinical Orientation. Biosynthesis of Pyrimidine: i. The synthesis of pyrimidine ring starts with the formation of carbamoyl phosphate from glutamine, ATP and CO2 being catalyzed by carbamoyl phosphate synthetase, present in the cytosol of the cell. ii. Carbamoyl phosphate [...]
In this article we will discuss about the Metabolism of Purine Nucleotides:- 1. Sources of the Various Atoms of the Purine Base 2. Biosynthesis of Purine Nucleotides [DE NOVO] 3. Salvage Reaction 4. Catabolism 5. Formation of Uric Acid. Contents: Sources of the Various Atoms of the Purine Base Biosynthesis of Purine Nucleotides [DE NOVO] Salvage Reaction of Purine Nucleotides [...]
The following points highlight the top seven applications of recombinant DNA technology in molecular analysis of disease. The applications are: 1. Normal Gene Variations 2. Gene Variations Causing Disease 3. Point Mutations 4. Deletions, Insertions and Rearrangements of DNA 5. Pedigree Analysis 6. Restriction Fragment Length Polymorphism (RFLP) 7. Gene Therapy. Applications of Recombinant DNA Technology: Normal Gene Variations Gene [...]