In this article we will discuss about the replication of picomavirus. The virion RNA is infectious and serves as both the genome and viral messenger RNA. The internal ribosome entry site (IRES) allows direct translation of the polyprotein. The polyprotein is initially processed by the viral protease(s) into various precursor and mature proteins to yield the structural proteins, replicase, VPg, [...]
In this article we will discuss about the replication of influenza viruses. Influenza virus is transmitted from infected mammals through the air by sneezing. Sneezing creates aerosols which consist of several virus particles. Besides, influenza is also transmitted by saliva, nasal secretions, blood and faeces. Moreover, it also spreads through droppings of infected birds. These bodily fluids or contaminated surfaces [...]
In this article we will discuss about the replication of reoviruses. The virus can enter the host cell via a receptor on the cell surface. The receptor is not known but is thought to include sialic acid (haeinagglutination, broad cell tropism), and junctional adhesion molecules (JAMs). Virus particles are internalized and partially uncoated by proteases in the endo-lysosomes/lysosomes in the [...]