Giardia intestinalis inhabiting in the lumen of intestine is a cosmopolitan parasite causing chronic diarrhoea of acute type and leads to malabsorp­tion in the intestine. This Giardia infection retards growth and development of children. The disease has been referred as a Giardiasis and it also has been indicated as a Zoonosis.

 

Giardia Species Commonly Found in Laboratory Animals

Treatment of Giardiasis:

i. Atebrin and acranil have been found to be used for Giardiasis.

ii. Chloroquine (300 mg per day) for five days is also reported to be effective.

iii. Metronidazole, a derivative of imidazole is also reported to be useful.

The Species of Giardia along with their Hosts other than Giardia Intestinalis:

i. Giardia agillis—Tadpole

ii. Giardia duodenalis—Rabbit

iii. Giardia caviae—Guinea-pig

iv. Giardia muris—Rat

The Salient Features of Cystic Stage of Giardia Intestinalis:

The fully formed Giardia intestinalis is oval in shape and it is 8-14 μm long and 7-10 μm broad and surrounded by a hyaline cyst wall. It contains four nuclei which may remain clustered at one end. The axostyles lie diagonally, forming a dividing line within the cyst wall.

Route of infection:

By ingestion of cysts (infective form)—with food and drink man is infected and this infection causes watery diar­rhoea and malabsorption.