Archive | Molecular Biology

Polysaccharides also occur in covalent combination with proteins and lipids. In the proteoglycans, the protein portion of the molecule represents only a small portion of the total molecular weight. These macromolecules are also known as mucopolysac­charides. Among the proteoglycans, one of the most extensively studied is cartilage proteoglycan, which is found extracellularly in cartilage and bone. In carti­lage proteoglycan (Fig. [...]

By convention, four levels of protein organization may be identified; these are called the primary, secondary, tertiary, and quaternary structures of the protein. 1. Primary Protein Structure: Successive amino acids forming the backbone of a polypeptide chain are linked together through peptide bonds and it is believed that these are the only covalent associations that occur between successive amino acids. [...]

Read this article to learn about Vertebrate Hemoglobin's: Structure, Function and Action ! Our understanding of the structure of the hemoglobin tetramer and the individual globin chains has advanced rapidly during the past 15 years, primarily because information about this molecule has been acquired through a variety of independent methods of investigation. These include: (1) X-ray crystallographic studies of hemoglobin [...]