There are five major immunoglobulin (Ig) classes namely: 1. IgG 2. IgA 3. IgD 4. IgM 5. IgE. Class # 1. IgG: (a) It constitutes 75% of the total serum immunoglobulin in human. (b) During the secondary immune response, it is the major Ig to be synthesized. Hence, it plays a vital role in the defense against infection. (c) It [...]
In this article we will discuss about the classification of immunoglobulin. 1. Isotypes: Based on the structure and sequence of their heavy-chain, constant regions, immunoglobulins are divided into five major groups called as classes which are again further subdivided into subclasses. In human, for example, there are five classes of immunoglobulins (commonly called GADME) viz., IgG, IgA, IgD, IgM [...]
The following points highlight the two main types of organs present in immune system of humans. The types are: 1. Primary Lymphoid Organs 2. Secondary Lymphoid Organs. Type # 1. Primary Lymphoid Organs: Primary lymphoid organs (PLO) are the major sites of lymphocyte development i.e. lymphopoiesis. Lymphocytes differentiate from lymphoid stem cells, proliferate and mature into functional cells called immuno-competent [...]