In this article we will discuss about the control of the synthesis of haemoglobin. 1. The Control of the Rate of Synthesis of the Peptide Chains. i. Rate of synthesis of Normal peptide chains: Approximately 95% of the red cell protein is haemoglobin. The peptide chains of haemoglobins are thus synthesized at a rate much higher than that of any [...]
In this article we will discuss about the genetics of thalassemia. There are two main types of thalassemia: α-thalassemia — resulting from a reduced rate of α-chain; β-thalassemia — resulting from a defective production of β-chains. More recently, family studies have revealed a heterogeneity of both α and β- thalassemia which is discussed in the Table 15.1. The β-thalassemias are [...]
In this article we will discuss about the diversity of retroviral oncogenes. Studies of other retroviruses of several different animal species (most notably the mouse, rat, chicken, and certain species of monkeys) soon led to the identification of other retroviral oncogenes. Over 20 different retroviral oncogene (Table 16.2) have been described to date, and more undoubtedly remain to be discovered. [...]