In this article we will discuss about the Mendel’s Principles. Also learn about its major limitations. Actually, the basic principles of heredity was formulated by Mendel in 1866 but under- standability and confirmation of Mendel's principles of heredity was clear to us after the rediscovery of Mendel's laws in 1900 by three geneticists : Correns, de Vries and Tschermark independently. [...]
In this article we will discuss about the regulation of levels of transcription by DNA methylation. In most higher plants and animals, the DNA is often modified after synthesis by the enzymatic conversion of many cytosine bases to 5-methylcytosine bases (Fig. 5.8). The extent of methylation varies from species to species; in mammals, from 2 to 7 percent of the [...]
In this article we will discuss about the structure of chromatin in the light of nucleosome. Preamble: A supercoil model for chromatin structure was originally described by Pardon and Wilkins in 1972. Later studies of Boldwin (1975), Kornberg (1974) and others have shown that such a sub-unit structure of chromatin is not only present in mammalian cells but also found [...]