The following points highlight the three main stages for mechanism of induced mutagenesis. The stages are: 1. Base Analogue Incorporation 2. Base Alteration 3. Distortion of DNA. Stage # 1. Base Analogue Incorporation: Some chemical compounds are sufficiently similar to the nitrogen bases of DNA so that they occasionally are incorporated into DNA in place of normal bases, such compounds [...]
Learn about the relationship between Gene and Enzyme. An understanding of the relationship of the gene and the enzyme is crucial for an analysis of the basis of growth and development of an organism. It has been established through varied lines of evidences that genes control all hereditary characters of an organism, which are transmitted from generation to generation. Simultaneously, [...]
Genes that confer the ability to convert cells to a tumourigenic state are called oncogenes. Cancer cells are characterised by immortalization, transformation and metastasis. Oncogenes induce uncontrolled cell growth resulting in tumour, so it can be anticipated that the products of these genes would act by stimulating cell division in some manner. Now it is clear that the products of [...]