The Watson-Crick model of DNA has been the basis for further work on DNA replication, mutation and recombination. Much evidence exists to establish the validity of this model. Nevertheless, the model has been scrutinized by other workers, and from time to time other models have been suggested by Wu (1970), Arnott (1968), Wang (1979) and a few others. Wang's model [...]
In this article we will discuss about the repeated sequence of chromosomal DNA. Eukaryotic genomes contain large amount of repetitive sequences, sometimes present in hundreds or thousands of copies per genome. The understanding of repetitive sequences is based on studies conducted on denaturation (separation of DNA double helix into its two component strands) and renaturation (re-association of the single strands [...]
In this article we will discuss about the uses of DNA microarrays. The DNA Microarray technology is used to determine the level of expression of many thousands of genes simultaneously. This new approach is used not for individual genetic loci, rather, for the analysis of genome-wide patterns of gene expression. Using DNA microarrays, it is possible to estimate the relative [...]