The Watson-Crick model of DNA has been the basis for further work on DNA replication, mutation and recombination. Much evidence exists to establish the validity of this model. Nevertheless, the model has been scrutinized by other workers, and from time to time other models have been suggested by Wu (1970), Arnott (1968), Wang (1979) and a few others. Wang's model [...]
In this article we will discuss about the repeated sequence of chromosomal DNA. Eukaryotic genomes contain large amount of repetitive sequences, sometimes present in hundreds or thousands of copies per genome. The understanding of repetitive sequences is based on studies conducted on denaturation (separation of DNA double helix into its two component strands) and renaturation (re-association of the single strands [...]
The process of DNA cloning is carried out in four ways: 1. DNA Cloning Inside Host Cell 2. Chemically by Polymerase Chain Reaction (PCR) 3. Reproductive Cloning 4. Therapeutic Cloning. Way # 1. DNA Cloning Inside Host Cell: DNA cloning is the selective amplification of a specific DNA fragment or a sequence for producing large quantities of the DNA fragment [...]