In this article we will discuss about the DNA replication in eukaryotes. In eukaryotes there are only two different types of DNA polymerases in contrast with DNA polymerase I, II and III of prokaryotes. Furthermore the DNA of eukaryotes is a long linear molecule with several replication units. A diploid mammalian cell contains on an average about 6 pg of [...]
In this article we will discuss about the introduction and mechanism of DNA replication. Introduction to DNA Replication: While presenting the double helical model of DNA, Watson and Crick had remarked, "It has not escaped our notice that the specific pairing (of bases) we have postulated suggests a possible copying mechanism for the genetic material." The complementary nature of the [...]
The following points highlight the three main types of bonds in DNA replication. The types are: 1. Covalent and Ionic Bonds 2. Hydrogen Bonds 3. Weak Chemical Bonds. Type # 1. Covalent and Ionic Bonds: Atoms can attain a more stable arrangement of electrons in their outermost shell by interacting with one another. An ionic bond results from transfer of [...]