The most common form of DNA which has right handed helix and proposed by Watson and Crick is called B-form of DNA or B-DNA. In addition, the DNA may be able to exist in other forms of double helical structure. These are A and C forms of double helix which vary from B- form in spacing between nucleotides and number [...]
In this article we will discuss about the Watson and Crick’s Model of Double Helix of DNA. Watson and Crick studied in advance the manuscript of Pauling and Corey in 1953. They concluded that: (i) Polynucleotide chain of DNA has a regular helix, (ii) The helix has a diameter of about 20 Å, and (iii) The helix makes a full [...]
In addition to organization of DNA in prokaryotes and lower eukaryotes, in eukaryotes the DNA helix is highly organised into the well-defined DNA-protein complex termed as nucleosomes. Among the proteins the most prominent are the histones. The histones are small and basic proteins rich in amino acids such as lysine and/or arginine. Almost in all eukaryotic cells there are five [...]