Study notes on Fidelity of Replication! Fidelity of replication means the faithful replication of DNA and the production of accurate daughter DNA using the parental DNA as a template. The accuracy of DNA replication is critical to cell reproduction. To produce a sequence of bases in the DNA of a daughter cell which is identical to that in the parent, [...]
The following points highlight the three main enzymes of DNA replications. The enzymes are: 1. Primase 2. DNA Polymerase 3. DNA Ligases. Enzyme # 1. Primase: A primase is an enzyme which makes the RNA primers required for initiation of Okazaki pieces on the lagging strand. Primase activity needs the formation of a complex of primase and at least six [...]
Let us make an in-depth study of the DNA replication:- Learn about: 1. Basic Features of DNA Replication 2. Mechanism of DNA Replication 3. Meselson and Stahl Experiment 4. Enzymes of DNA Replication 5. Formation of Replication Forks & Replication Bubbles and Others. Central Dogma: Genetic material is always nucleic acid and it is always DNA except some viruses. DNA [...]