Study notes on Fidelity of Replication! Fidelity of replication means the faithful replication of DNA and the production of accurate daughter DNA using the parental DNA as a template. The accuracy of DNA replication is critical to cell reproduction. To produce a sequence of bases in the DNA of a daughter cell which is identical to that in the parent, [...]
The following points highlight the three main enzymes of DNA replications. The enzymes are: 1. Primase 2. DNA Polymerase 3. DNA Ligases. Enzyme # 1. Primase: A primase is an enzyme which makes the RNA primers required for initiation of Okazaki pieces on the lagging strand. Primase activity needs the formation of a complex of primase and at least six [...]
The upcoming discussion will update you about the difference between Continuous and Discontinuous Replication. Difference # Continuous Replication: 1. Occurs on leading of a replication fork. 2. Starts at the beginning of replication. 3. Progresses in on direction, i.e., towards the replication fork. 4. Synthesis of DNA takes place continuously. 5. In vivo need no RNA primer. 6. Only DNA [...]