In this article we will discuss about the changes in chromatin structure during transcription. Displacement of nucleosomes: During transcription, some changes in the chromatin structure occur in the region of transcription. RNA polymerase is comparatively larger in size than the nucleosomes. The molecular weight of RNA polymerase is about 5,00,000 Daltons, while that of nucleosome is about 2,60,000 Daltons. Lewin [...]
In this article we will discuss about:- 1. Coiled DNA Model 2. Nucleosome-Solenoid Model of Chromatin Fibres. Coiled DNA Model: This model of chromatin structure was proposed by DuPraw in 1965. As per this model, DNA molecule is associated with three classes of proteins: (i) Lysine rich histories: They are common to both A and B type fibres and are [...]
The following points highlight the two main ways of representing chromosome set of species. The ways are: 1. Karyogram 2. Idiogram or Idiotype. Representing Chromosome: Way # 1. Karyogram: Photomicrographs of the chromosomes of a single representative somatic metaphase cell are clipped out and arranged in homologous pairs according to their size. If the chromosomes are small and there is [...]