In this article we will discuss about:- 1. Cellular Oncogenes Contain Introns 2. Conservation of Proto-Oncogenes during Evolution 3. Proto-Oncogene Products Key Regulators of Cell Division 4. Comparison of Viral Oncogenes with Cellular Proto-Oncogenes 5. Homology with Viral Oncogenes 6. Cancer Cells: Loss of Control of Cell Division. Cancer is a large class of diverse diseases, all of which exhibit [...]
In this article we will discuss about the chromosome abnormalities in human cancer cell. Many human cancer cells have chromosome abnormalities and frequently specific abnormalities are associated with specific forms of cancer. Chromosome abnormalities in human cancer cells can involve both the number and, more frequently, the structure of the chromosome. Number of abnormalities are mostly due to non-disjunction and [...]
The following points highlight the nine main biochemical mechanisms of action of growth factors of cancer cells. The biochemical mechanisms are: 1. Progression of Tumors 2. Drugs used in Cancer Chemotherapy 3. P-Glycoprotein Plays an Important Role in Multidrug Resistance in Cancer Chemotherapy 4. Metastasis 5. Isolation of a Number of Genes Involved in the Increased Susceptibility to Cancer and [...]