Read this article to learn about the features and methods of genetic improvement of strains. In general, the wild strains of microorganisms produce low quantities of commercially important metabolites, although the yield can be increased by optimizing the fermentation conditions. The potentiality of the metabolite formation is genetically determined. Therefore, genetic improvements have to be made and new strains developed [...]
Read this article to learn about the features and operations of a conventional bioreactor. Features of a Conventional Bioreactor: The different types and designs of bioreactors are described. The most common features of a typical bioreactor are diagrammatically represented in Fig. 19.5, and briefly described hereunder. Conventional bioreactors are cylindrical vessels with domed top and bottom. The reaction vessel, surrounded [...]
Read this article to learn about the various methods for sterilization of media and air. Sterilization of Culture Media and Gases: For successful fermentation, it is absolutely essential to ensure: a. Sterility of the media containing the nutrients. b. Sterility of incoming and outgoing air. c. Sterility of the bioreactor. d. Prevention of contamination during fermentation. A bioreactor can be [...]