The following points highlight the three important examples of transgenic animal. The examples are: 1. Cloning Dolly 2. Transgenic Mice 3. Reporter System. Example # 1. Cloning Dolly: In February 1996, Ian Wilmut and co-workers from the Roslin Institute and PPL Therapeutics, both in Edinburgh, Scotland, reported in Nature journal that they had successfully cloned a sheep from a cell [...]
The following points highlight the top five benefits of transgenic animals. The benefits are: 1. Normal Physiology and Development 2. Study of Disease 3. Biological Products 4. Vaccine Safety 5. Chemical Safety Testing. Benefit # 1. Normal Physiology and Development: Transgenic animals can be specifically designed to allow the study of how genes are regulated and how they affect the [...]
This article throws light upon the five principal methods used for creation of transgenic animals. The five principal methods are: (1) Physical Transfection (2) Chemical Transfection (3) Retrovirus-Mediated Gene Transfer (4) Virus Vector and (5) DNA Packaged inside a Bacterium. Method # 1. Physical Transfection: This method involves the direct microinjection of a chosen gene construct (a single gene or [...]