The upcoming discussion will update you about the difference between Metabolic Acidosis and Respirator Acidosis.
Difference # Metabolic Acidosis:
1. Bicarbonate (HCO3–) deficit.
2. pH lowered.
3. Respiratory-low pH stimulates respiratory centre causing decrease in [H2CO3].
4. Urinary pH-acidic.
5. Abnormal increase in anions due to endogenous production of acid ions, ingestion of acidifying salts, and renal insufficiency.
6. Abnormal loss of HCO3–, e.g., in severe diarrhoea.
Difference # Respiratory Acidosis:
1. Carbonic acid excess.
2. pH lowered.
3. The most important renal mechanism causes increase in H+-Na4 exchange, increased ammonia formation.
4. Urinary pH-acidic.
5. Depression of respiration due to damage to CNS, loss of ventilatory functions, effects of pain like pleurisy.
6. Impairment of diffusion of CO2 across alveolar membrane, obstruction to escape of CO2 from alveoli, insufficient pulmonary blood flow.