In this article we will discuss about the meaning of tRNA. The genetic message contained in the nucleotide sequence of transcribed RNA cannot be read off directly by the amino acids in the polypeptide chain. Crick and Hoagland were first to postulate that an intermediate RNA molecule functions as an "adaptor" into which the amino acid is plugged so that [...]
In this article we will discuss about the processing of pre-tRNA in E.coli and yeast. In prokaryotes, there are many operons (e.g. 7 genes in E. coli) which are separated by spacer sequences. Mature tRNA molecules are generated by processing longer pre-tRNA transcripts. Through a specific step, RNases D, E, F and P generate these mature tRNA molecules by exo-and [...]
The below mentioned article provides a short note on the aminoacylation of tRNA. Role of Transfer RNA: Transfer RNA molecules play a key role in the process by delivering amino acids to the ribosome in an order specified by the mRNA sequence; this ensures that the amino acids are joined together in the correct order. Cells usually contain many species [...]