The following points highlight the three possibilities of the transformation of pyruvic acid. The possibilities are: 1. Production of Lactic Acid 2. Alcoholic Fermentation 3. Formation of α-Glycerophosphate and Glycerol. Possibility # 1. Production of Lactic Acid: In animals, in muscle cells (where anaerobiosis conditions often prevail when oxygen utilization is more rapid than its input in cells) or in [...]
In this article we will discuss about the meaning of transformation. Transformation is the process of adding a foreign DNA fragment from a donor genome into genome of a recipient cell. The donor fragment passes through the cell membrane of the recipient cell (which may or may not belong to the same species) and becomes incorporated into the latter's genome [...]
In this article we will discuss about:- 1. Discovery of Transformation 2. Process of Transformation 3. Competence 4. Linkage and Gene Mapping. Discovery of Transformation: The phenomenon was first discovered in 1928 from Griffiths experiment with Diplococcus pneumoniae. As this historical experiment has been instrumental for identification of DNA as a hereditary material. Briefly, when a suspension containing a mixture [...]