Transcription in Higher Eukaryotes | Genetics
In this article we will discuss about the mechanisms of regulation of transcription in higher eukaryotes. In E. coli, the RNA polymerase holoenzyme (with sigma factor) contains all the information needed to accurately initiate transcription given proper promoter signals (-35 recognition sequence plus -10 Pribnow box). However, RNA polymerase II of eukaryotes, which transcribes most of the protein- encoding nuclear [...]