Strain Improvement of Microorganisms | Microbiology
In this article we will discuss about the improvement of microbial strains for better production of products. 1. Methods of Strain Improvement: A mutant requiring oleic acid for neomycin formation by Streptomyces fradiae showed a decrease in the intracellular level of neomycin precursors in the mutant. On the other hand supersensitive mutants of β-lactam antibiotics are another example. Recent approaches [...]