Abnormal Hemoglobin Derivatives| Biochemistry

The following points highlight the three major derivatives of abnormal hemoglobin. The derivatives are: 1. Met-hemoglobin 2. Sulfhemoglobin 3. Carboxyhemoglobin. Derivative # 1. Met-hemoglobin: a. This is an oxidized hemoglobin (ferrous iron is oxidized to ferric iron). Oxygen is in firm combination. b. It is incapable of functioning as an oxy­gen carrier. Cyanosis usually develops when the concentration of it [...]