Causes for the Oncogenicity | Genetics

In this article we will discuss about causes for the oncogenicity of the onco­gene. When the oncogene from human bladder carcinoma cells was sequenced, and its sequence was compared with the sequence of the homologous proto-oncogene, its onco­genicity was found to result from a single base pair substitution. That is, a single base pair difference was shown to correlate with [...]